Submitted by gwsAdmin on Fri, 05/03/2010 - 11:55
Mycobacterium bovis in the Environment: Towards our Understanding of its Biology
O Courtenay, E M H Wellington
1. November 2008
Bovine tuberculosis (bTB) is a persistent problem in cattle herds in Great Britain and Ireland. Whilst the
involvement of badgers in the transmission cycle of Mycobacterium bovis is well established, the route of
transmission from wildlife to cattle and visa versa is not understood sufficiently to inform day-to-day
management of transmission risks on the farm. Recent detection of M. bovis in soil on a large proportion of farms
in bTB endemic regions highlights the possibility that an environmental reservoir of M. bovis may exist to help
maintain bTB persistence even in regions void of badgers. Until recently, technical difficulties have excluded
study of M. bovis in its in situ metabolic state which is necessary in order to understand its potential
epidemiological significance. Here we describe important advances in this field.
Keywords: Bovine tuberculosis, environmental mycobacteria, infectious disease, badgers, transmission, cell viability, survival, infectivity
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